Phosphorylation induces the cytoplasmic deposition of TAZ and its own degradation

Phosphorylation induces the cytoplasmic deposition of TAZ and its own degradation. in cancers therapy. We used 18 606 little chemical substances to individual osteosarcoma U2Operating-system cells expressing GFP\fused TAZ (GFP\TAZ), supervised the subcellular localization of GFP\TAZ, and chosen 33 substances that shifted GFP\TAZ towards the cytoplasm. Unexpectedly, just a limited … Continue reading Phosphorylation induces the cytoplasmic deposition of TAZ and its own degradation